방사선의학 웹진

바로가기  >

Fig. 1. 

Transaxial [¹⁸F]Mefway PET images. Time-averaged images are shown between (A) 0 and 20 min, (B) 20 and 40 min, (C) 40 and 60 min, (D) 60 and 80 min, (E) 80 and 100 min, and (F) 100 and 120 min.

Fig. 4. 

Relationship between DVR and SUVR for [¹⁸F]Mefway in each time interval. (A) 0–20 min, (B) 20–40 min, (C) 40–60 min, (D) 60–80 min, (E) 80–100 min, and (F) 100–120 min. 

Abstract

To determine the optimal acquisition time of [(18)F]Mefway PET, we examined the regional specific-to-nonspecific binding ratios and evaluated the relationship between distribution volume ratios (DVRs) and standardized uptake value ratios (SUVRs) in various time windows. The specific-to-nonspecific binding ratios peaked after 40min and there was a strong correlation between DVR and SUVR in the 60-80min. Therefore, we recommend the use of a single time point between 60 and 80min for [(18)F]Mefway static PET. 

Author information

Lee JH1, Ryu YH1, Lyoo CH2, Choi SH3, Kim JJ4, Choi JY5.​

1Department of Nuclear Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

2(c)Department of Psychiatry and Institute of Human Behavioral Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.

3(d)Department of Psychiatry and Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.

4(b)Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

5Department of Nuclear Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address: smhany@yuhs.ac.