방사선의학 웹진

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Abstract

The purpose of this study was to estimate average radiation exposure from (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) examinations and to analyze possible factors affecting the radiation dose. A nation-wide questionnaire survey was conducted involving all institutions that operate PET/CT scanners in Korea. From the response, radiation doses from injected FDG and CT examination were calculated. A total of 105 PET/CT scanners in 73 institutions were included in the analysis (response rate of 62.4%). The average FDG injected activity was 310 ± 77 MBq and 5.11 ± 1.19 MBq/kg. The average effective dose from FDG was estimated to be 5.89 ± 1.46 mSv. The average CT dose index and dose-length product were 4.60 ± 2.47 mGy and 429.2 ± 227.6 mGy∙cm, which corresponded to 6.26 ± 3.06 mSv. The radiation doses from FDG and CT were significantly lower in case of newer scanners than older ones (P < 0.001). Advanced PET technologies such as time-of-flight acquisition and point-spread function recovery were also related to low radiation dose (P < 0.001). In conclusion, the average radiation dose from FDG PET/CT is estimated to be 12.2 mSv. The radiation dose from FDG PET/CT is reduced with more recent scanners equipped with image-enhancing algorithms. 

Author information

Kwon HW1, Kim JP2, Lee HJ2, Paeng JC3, Lee JS2, Cheon GJ3, Lee DS4, Chung JK3, Kang KW3.​

1Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Korea.; Department of Molecular Medicine and Biopharmaceutical Science, Graduate school of Convergence Science and Technology, Seoul National University, Seoul, Korea.

2Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Korea .

3Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Korea.; Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea.

4Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Korea.; Department of Molecular Medicine and Biopharmaceutical Science, Graduate school of Convergence Science and Technology, Seoul National University, Seoul, Korea.; Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea.