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  • [Med Phys.] 자궁 내막종양 전자선근접방사선치료를 위한 3차원 프린팅 어플리케이터 제작 연구Three-dimensional-printed vaginal applicators for electronic brachytherapy of endometrial cancers.

    KAIST / 이주혁, 조성오*

  • 출처
    Med Phys.
  • 등재일
    2019 Feb
  • 저널이슈번호
    46(2):448-455. doi: 10.1002/mp.13335. Epub 2018 Dec 31.
  • 내용

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    Abstract
    PURPOSE:
    Vaginal applicators for a novel miniature x-ray tube were developed using three-dimensional (3D) printing to be used in brachytherapy of endometrial cancers.

    METHODS:
    Cylindrical vaginal applicators with various diameters, lengths, and infill percentages (IFPs) were fabricated using a 3D printer. X-ray dose distributions and depth-dose profiles were calculated using a Monte Carlo simulation. The performances of the applicators were evaluated by measuring and analyzing the dosimetric characteristics of x rays generated from the miniature x-ray tube equipped with the applicators.

    RESULTS:
    Quite uniform dose distributions around the applicators were achieved by optimizing the dwell positions and the dwell times of the miniature x-ray tube inside the applicators. In addition, identical absolute dose and depth-dose profiles were obtained through the control of the IFP values even though different-sized applicators are used.

    CONCLUSION:
    The presented 3D printing technique provides an efficient approach to provide vaginal applicators with optimal IFPs that allow consistent treatment time for patients of varying vaginal canal size.

     


    Author information

    Lee JH1, Kim HN1, Lim HS1, Cho SO1.
    1
    Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Republic of Korea.

  • 키워드
    3D printing; electronic brachytherapy; endometrial cancer; miniature x-ray tube; vaginal applicator
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