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  • [Phys Med Biol. ] Total body irradiation with a compensator fabricated using a 3D optical scanner and a 3D printer.

    2017년 06월호
    [Phys Med Biol. ] Total body irradiation with a compensator fabricated using a 3D optical scanner and a 3D printer.

    서울대병원/ 박소연, 박종민*

  • 출처
    Phys Med Biol.
  • 등재일
    2017 May 7
  • 저널이슈번호
    62(9):3735-3756. doi: 10.1088/1361-6560/aa6866. Epub 2017 Mar 22.
  • 내용

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    (a)3D 프린터로 제작된 3D 보상체 제작용 주조틀과 (b)주조된 3D 보상체
      

    인체 팬톰의 (a)머리, (b), (c)어깨, (d)흉부, (e)복부, (f)엉덩이 부위에 대하여 측정하였고, 3D 보상체를 사용하였을 때 기존 보상체보다 균일한 방사선량을 전달 할 수 있었음. 


    Abstract

    We propose bilateral total body irradiation (TBI) utilizing a 3D printer and a 3D optical scanner. We acquired surface information of an anthropomorphic phantom with the 3D scanner and fabricated the 3D compensator with the 3D printer, which could continuously compensate for the lateral missing tissue of an entire body from the beam's eye view. To test the system's performance, we measured doses with optically stimulated luminescent dosimeters (OSLDs) as well as EBT3 films with the anthropomorphic phantom during TBI without a compensator, conventional bilateral TBI, and TBI with the 3D compensator (3D TBI). The 3D TBI showed the most uniform dose delivery to the phantom. From the OSLD measurements of the 3D TBI, the deviations between the measured doses and the prescription dose ranged from  -6.7% to 2.4% inside the phantom and from  -2.3% to 0.6% on the phantom's surface. From the EBT3 film measurements, the prescription dose could be delivered to the entire body of the phantom within  ±10% accuracy, except for the chest region, where tissue heterogeneity is extreme. The 3D TBI doses were much more uniform than those of the other irradiation techniques, especially in the anterior-to-posterior direction. The 3D TBI was advantageous, owing to its uniform dose delivery as well as its efficient treatment procedure.

     

    Author information

    Park SY1, Kim JI, Joo YH, Lee JC, Park JM.

    1Department of Radiation Oncology, Seoul National University Hospital, Seoul 03080, Republic of Korea. Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul 03080, Republic of Korea. Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Republic of Korea. Center for Convergence Research on Robotics, Advanced Institutes of Convergence Technology, Suwon 16229, Republic of Korea. 

     

  • 연구소개
    최신 기술인 3D printer와 3D scanner를 이용한 환자맞춤형 전신방사선조사 보상체 제작 및 효용성 검증을 수행한 논문입니다. 환자 전신에 균일한 방사선량을 조사해야하는 전신방사선조사 목표를 위해 일반적으로 제작되는 전신방사선조사 보상체는 환자의 굴곡진 체형을 제대로 반영하기 어려워 균일한 선량전달이 불가능합니다. 따라서, 환자 외형정보를 적용하여 환자맞춤형 3D 보상체를 개발하였고 인체 팬톰을 통하여 측정하였을 시, 기존 보상체보다 환자 전신에 대하여 3%로 이내의 균일한 방사선량을 전달 할 수 있었습니다.
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