방사선의학 웹진

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Abstract

BACKGROUND:

The purpose of this retrospective study was to assess the diagnostic value of 18 F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT and the prognostic value of metabolic PET parameters in patients with adenoid cystic carcinoma of the head and neck (ACCHN).

METHODS:

Forty patients with newly diagnosed ACCHN were enrolled in this study. We investigated the diagnostic value of 18 F-FDG PET/CT for detecting and staging compared to conventional CT. Kaplan-Meier survival analysis for progression-free survival (PFS) was performed with clinicopathological factors and metabolic PET parameters.

RESULTS:

The 18 F-FDG PET/CT showed comparable sensitivity (92.3%) to conventional CT for lesion detection, and changed staging and management plan in 6 patients (15.0%). Lower PFS rates were associated with advanced T classification, advanced TNM classification, high maximum standardized uptake value (SUVmax; >5.1), and high total lesion glycolysis (>40.1) of the primary tumor.

CONCLUSION:

The 18 F-FDG PET/CT can provide additional information for initial staging, and metabolic PET parameters may serve as prognostic factors of ACCHN. 

Author information

Jung JH1, Lee SW1, Son SH1, Kim CY1, Lee CH1, Jeong JH1, Jeong SY1, Ahn BC1, Lee J1,2.

1 Department of Nuclear Medicine, Kyungpook National University Medical Center and School of Medicine, Daegu, Republic of Korea.

2 DGMIF, Daegu, Republic of Korea.