방사선의학 웹진

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Abstract
Association of blood pool (BP) and adipose tissue activity from F-18 fluorodeoxyglucose positron-emission tomography/computed tomography (FDG PET/CT) with the parameters of metabolic syndrome (MetS) and different MetS/obesity types were investigated. 245 subjects underwent FDG PET/CT scan for health check-ups were investigated retrospectively. Associations of BP (BP SUV: SUVmax, SUVmean), visceral (VAT SUV), and subcutaneous adipose tissue (SAT SUV) activity with parameters of MetS, body mass index (BMI), and lipid profiles were analyzed. MetS/obesity types were subdivided into metabolically healthy obese (MHO) and metabolically unhealthy obese (MUO). BP SUV was higher in subjects with MetS (t-test, P < 0.005), and was associated with MetS from multivariable binary logistic regression (OR 5.232 P = 0.010). BP SUV was statistically higher in MUO than in MHO (P < 0.05) along with blood pressure, triglycerides, and HDL-cholesterol. Multivariable binary logistic regression analysis showed MUO had higher blood pressure and BP SUV, while lower HDL-cholesterol relative to MHO after adjusting for triglycerides.

Affiliations

Ji-In Bang  1 , Chang Mo Moon  2 , Hye Ok Kim  3 , Seo Young Kang  3 , Hai-Jeon Yoon  4 , Bom Sahn Kim  5
1 Department of Nuclear Medicine, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
2 Depratment of Internal Medicine, Ewha Womans University School of Medicine, Seoul, South Korea.
3 Department of Nuclear Medicine, Ewha Womans University School of Medicine, Seoul, South Korea.
4 Department of Nuclear Medicine, Ewha Womans University School of Medicine, Seoul, South Korea. haijeon.yoon@gmail.com.
5 Department of Nuclear Medicine, Ewha Womans University School of Medicine, Seoul, South Korea. kbomsahn@ewha.ac.kr