바로가기  >

Abstract
BACKGROUND AND PURPOSE:
Delineation of clinical target volumes (CTVs) remains a weak link in radiation therapy (RT), and large inter-observer variation is seen. Guidelines for target and organs at risk delineation for prostate cancer in the primary setting are scarce. The aim was to develop a delineation guideline obtained by consensus between a broad European group of radiation oncologists.

MATERIAL AND METHODS:
An ESTRO contouring consensus panel consisting of leading radiation oncologists and one radiologist with known subspecialty expertise in prostate cancer was asked to delineate the prostate, seminal vesicles and rectum on co-registered CT and MRI scans. After evaluation of the different contours, literature review and multiple informal discussions by electronic mail a CTV definition was defined and a guide for contouring the CTV of the prostate and the rectum was developed.

RESULTS:
The panel achieved consensus CTV contouring definitions to be used as guideline for primary RT of localized prostate cancer.

CONCLUSION:
The ESTRO consensus on CT/MRI based CTV delineation for primary RT of localized prostate cancer, endorsed by a broad base of the radiation oncology community, is presented to improve consistency and reliability.

Author information

Salembier C1, Villeirs G2, De Bari B3, Hoskin P4, Pieters BR5, Van Vulpen M6, Khoo V7, Henry A8, Bossi A9, De Meerleer G10, Fonteyne V11.
1
Department of Radiation Oncology, Europe Hospitals Brussels, Belgium.
2
Department of Radiology, Ghent University Hospital, Belgium.
3
Department of Radiation Oncology, CHRU Besançon, France.
4
Mount Vernon Cancer Centre, Northwood, United Kingdom.
5
Department of Radiation Oncology, Academic Medical Center/University of Amsterdam, The Netherlands.
6
Department of Radiation Oncology, University Medical Center Utrecht, The Netherlands.
7
Department of Clinical Oncology, Royal Marsden Hospital, London, United Kingdom.
8
Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, United Kingdom.
9
Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France.
10
Department of Radiation Oncology, University Hospital Leuven, Belgium.
11
Department of Radiation Oncology, Ghent University Hospital, Belgium. Electronic address: Valerie.fonteyne@uzgent.be.