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  • [Acta Otolaryngol.] Assessment of radiation-induced otitis media in patients with parotid gland malignancy

    연세의대 / 나지나, 배성훈*

  • 출처
    Acta Otolaryngol.
  • 등재일
    2021 May
  • 저널이슈번호
    141(5):466-470. doi: 10.1080/00016489.2021.1892184.
  • 내용

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    Abstract
    Background: Otitis media with effusion (OME) is a known side effect of radiation therapy in patients with head and neck cancer.

    Aims/objectives: To investigate the incidence rate and clinical course of radiation-induced OME, we have reported on the long-term characteristics of OME in patients with parotid gland malignancy.

    Material and methods: This cohort study assessed 200 patients who underwent post-parotidectomy radiation therapy from January 2010 to December 2019 in a tertiary referral center. Postoperative radiation therapy was performed at 6 weeks post-surgery. Serial magnetic resonance images were collected to detect otitis media. Two blinded otologists individually assessed data from radiation therapy initiation to 36 months of post-radiation therapy.

    Results: A total of 121 patients were enrolled (male, 61 [50.4%]; mean age, 46.98 ± 15.69 years), of which 14 developed otitis media (11.6%) within 6 months after radiation therapy. Spontaneous remission occurred without intervention within 1 year, excluding one patient who sustained otitis media for 2 years.

    Conclusions and significance: Radiation-induced OME occurred in 11.6% of patients and it remitted within 1 year without intervention. Therefore, cooperation between otolaryngologists and radiation oncologists is required and invasive intervention should be considered with careful risk-benefit evaluation.

     

     

    Affiliations

    Gina Na  1   2 , Kyung Hwan Kim  3 , Hwa Kyung Byun  3 , Seong Hoon Bae  1
    1 Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.
    2 Department of Otorhinolaryngology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
    3 Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Republic of Korea.

  • 키워드
    Parotid neoplasms; otitis media; radiotherapy.
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