글로벌 연구동향
의학물리학
- 2025년 09월호
[Med Phys .] X-ray CT metal artifact reduction using neural attenuation field prior연세대 / 이주호, 백종덕*
- 출처
- Med Phys .
- 등재일
- 2025 Jul
- 저널이슈번호
- 52(7):e17859.
- 내용
Abstract
Background: The presence of metal objects in computed tomography (CT) imaging introduces severe artifacts that degrade image quality and hinder accurate diagnosis. While several deep learning-based metal artifact reduction (MAR) methods have been proposed, they often exhibit poor performance on unseen data and require large datasets to train neural networks.Purpose: In this work, we propose a sinogram inpainting method for metal artifact reduction that leverages a neural attenuation field (NAF) as a prior. This new method, dubbed NAFMAR, operates in a self-supervised manner by optimizing a model-based neural field, thus eliminating the need for large training datasets.
Methods: NAF is optimized to generate prior images, which are then used to inpaint metal traces in the original sinogram. To address the corruption of x-ray projections caused by metal objects, a 3D forward projection of the original corrupted image is performed to identify metal traces. Consequently, NAF is optimized using a metal trace-masked ray sampling strategy that selectively utilizes uncorrupted rays to supervise the network. Moreover, a metal-aware loss function is proposed to prioritize metal-associated regions during optimization, thereby enhancing the network to learn more informed representations of anatomical features. After optimization, the NAF images are rendered to generate NAF prior images, which serve as priors to correct original projections through interpolation. Experiments are conducted to compare NAFMAR with other prior-based inpainting MAR methods.
Results: The proposed method provides an accurate prior without requiring extensive datasets. Images corrected using NAFMAR showed sharp features and preserved anatomical structures. Our comprehensive evaluation, involving simulated dental CT and clinical pelvic CT images, demonstrated the effectiveness of NAF prior compared to other prior information, including the linear interpolation and data-driven convolutional neural networks (CNNs). NAFMAR outperformed all compared baselines in terms of structural similarity index measure (SSIM) values, and its peak signal-to-noise ratio (PSNR) value was comparable to that of the dual-domain CNN method.
Conclusions: NAFMAR presents an effective, high-fidelity solution for metal artifact reduction in 3D tomographic imaging without the need for large datasets.

Affiliations
Jooho Lee 1, Seongjun Kim 2, Junhyun Ahn 2, Adam S Wang 3, Jongduk Baek 1
1Department of Artificial Intelligence, Yonsei University, Seoul, Republic of Korea.
2School of Integrated Technology, Yonsei University, Seoul, Republic of Korea.
3Department of Radiology, Stanford University, California, USA.
- 키워드
- 3D deep learning; metal artifact reduction; neural field; sinogram inpainting; x‐ray CT.
- 연구소개
- 최근 인공지능(AI) 기반 3차원 의료영상처리에서 주목받는 Neural Attenuation Field(NAF)를 활용하여 새로운 금속 인공음영 저감 기법(MAR)을 제안한 연구입니다. 본 논문은 데이터 집약적 학습 대신 단일 데이터를 이용한 최적화 기반 학습으로 고품질 prior 영상을 생성하고, 이를 바탕으로 금속 인공음영을 효과적으로 저감할 수 있음을 보여줍니다. 본 연구는 딥러닝과 기존 물리 모델을 융합한 시도로, 향후 관련 연구에 좋은 참고가 되었으면 좋겠습니다.
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