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  • Development and verifcation of LEP 300 kilovoltage radiotherapy system for companion animals

    연세의대 / 권나혜, 김동욱*

  • 출처
    Journal of the Korean Physical Society
  • 등재일
    2022 18 August
  • 저널이슈번호
  • 내용

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    Abstract
    The Life Extension for Pets (LEP) 300 is a radiotherapy system developed by the AURA CARE Company for companion animals. For the performance evaluation of LEP 300 kilovoltage treatment equipment, which is the purpose of this study, we conducted acceptance tests and beam commissioning using water-equivalent solid phantom, Gafchromic EBT3 film, and an ion chamber. We investigated the mechanical functionality, such as gantry angle accuracy, couch accuracy, half-value layer (HVL), field size accuracy, and alignment. We measured the absolute dose, percent depth dose (PDD), beam profile for the full width at half maximum (FWHM), flatness, asymmetry, penumbra, and output factor to evaluate the beam characteristic. The main measurement value was input to the Radiation Treatment Planning (RTP) software and used for calculations and compared with other independent data measured. Most of the measured values for mechanical checks were within the tolerances of the medical linear accelerator (LINAC). The output of the beam was 1.295 Gy/min at a depth of 2 cm, and the difference between the PDD data and the RTP system was within 2.134%. The penumbra difference between the measured profile data and RTP was within 1.02 cm in the 10 × 10 cm2 field. We confirmed the mechanical accuracy and dosimetry characteristics of the LEP 300 kV radiotherapy equipment. However, the global errors of the profile outside of the penumbra were significantly higher, at a maximum of 11.6%. They were caused by the low dose effects under 300 kV energy. In the future, it is thought that it will be possible to increase the accuracy of the RTP system through the improvement of the dose calculation algorithm. We think our study results will help establish a quality verification standard for the kV energy area and a systematic protocol for the periodic management of equipment.

     

     

    Affiliation

    Na Hye Kwon1,2 · Jinsung Kim1,2,3 · Dong Oh Shin1, Dong Wook Kim1,2 · Hyeon Tae Kyeong4, Dae Woon Kim4, Weonkuu Chung5, Dong Ho Shin6

    1 Department of Radiation Oncology, Yonsei Cancer Center,
    Heavy Ion Therapy Research Institute, Yonsei University
    College of Medicine, Seoul 03722, Korea
    2 Medical Physics and Biomedical Engineering Lab (MPBEL),
    Yonsei University College of Medicine, Seoul 03722, Korea
    3 Oncosoft Inc, Seoul 03787, Korea
    4 Research Institute, AURACARE, Siheung 17095, Korea
    5 Department of Oncology, Kyung Hee University Hospital
    at Gangdong, Seoul 05278, Korea
    6 Proton Therapy Center, National Cancer Center,
    Koyang 10408, Korea

  • 키워드
    Radiotherapy equipment ; Companion animal ; Beam commissioning ; Acceptance test ; kV energy
  • 편집위원

    본 연구는 프로토타입 동물용 방사선치료 시스템의 개발 및 특성을 확립한 연구로 LEP 300 은 아우라케어 연구진, 의학물리학자, 의사들의 협업을 통해 개발된 자체자폐형 치료기입니다. Acceptance test와 Commissioning 을 통해 장비의 기계적, 선량적 특성을 확립하였습니다.

    2022-10-06 19:05:52

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