의학물리학

본문글자크기
  • [Med Phys.] Method to estimate fan-beam CT noise power spectrum using two basis functions with a limited number of noise realizations

    [Med Phys.] Method to estimate fan-beam CT noise power spectrum using two basis functions with a limited number of noise realizations

    연세대 / 장한주, 백종덕*

  • 출처
    Med Phys.
  • 등재일
    2022 Mar
  • 저널이슈번호
    49(3):1619-1634. doi: 10.1002/mp.15445. Epub 2022 Jan 31.
  • 내용

    바로가기  >

    Abstract
    Purpose: The noise power spectrum (NPS) plays a key role in image quality (IQ) evaluation as it can be used for predicting detection performance or calculating detective quantum efficiency (DQE). Traditionally, the NPS is estimated by ensemble averaging multiple realizations of noise-only images. However, the estimation error increases when there are a limited number of images. Since the estimation error directly affects the image quality (IQ) index, an accurate NPS estimation method is required. Recent works have proposed NPS estimation methods using the radial one-dimensional (1D) NPS as the basis; however, when sharp kernels are used during image reconstruction, these methods cannot accurately estimate the amplitude of each angular spoke of the 2D NPS composed of different cutoff frequencies determined from the complementary projection magnification factors for different spatial regions. In this work, we propose a 2D NPS estimation method that reflects the accurate amplitude of each angular spoke for fan-beam CT images.

    Methods: An angular spoke of the 2D NPS is composed of two basis functions with different cutoff frequencies determined from the complementary projection magnification factors. The proposed method estimates these two weighting factors for each basis function by minimizing the mean-squared error (MSE) between the 2D NPS estimated from 10 noise realizations. Two noise profiles and two types of apodization filters (i.e., rectangular and Hanning) were used to reconstruct the noise-only images. To examine the nonstationary noise property of fan-beam CT images, the 2D NPS was estimated at three different local regions. The estimation accuracy of the proposed method was further improved by estimating the approximate weighting factors with sinusoidal functions, considering that the weighting factors vary slowly throughout the view angles. Regression orders of 1 to 4 were used during these estimations. The approximate weighting factors were then multiplied with each of the basis functions to estimate the 2D NPS. The normalized mean-squared error (NMSE) was used as an index to compare the performance of each NPS estimation method, with the analytical 2D NPS as the reference. Further validation was performed using XCAT phantom data.

    Results: We observed that the 2D NPS estimated using two basis functions reflected the accurate amplitude of each angular spoke, whereas the 2D NPS estimated using the radial 1D NPS as the basis could not. The 2D NPS estimated by applying the approximate weighting factors showed improved performance compared with that estimated using two basis functions. In addition, unlike the view-independent noise cases, where a lower regression order showed higher estimation performance, a higher regression order showed higher estimation performance in the view-dependent noise cases.

    Conclusions: In this work, we propose a 2D NPS estimation method that reflects the accurate amplitude of each angular spoke for fan-beam CT images using two basis functions. We observed that the proposed 2D NPS estimation method using two basis functions achieved better estimation performance compared with the method using the radial 1D NPS as the basis.

     

     

     


    Affiliation

    Hanjoo Jang  1 , Jongduk Baek  1
    1 School of Integrated Technology, Yonsei University, Incheon, South Korea.

  • 키워드
    approximate weighting factors; estimation accuracy; fan-beam CT; noise power spectrum (NPS); nonstationary noise; two basis functions.
  • 연구소개
    컴퓨터 단층촬영 (CT) 영상의 잡음 특성을 이해하는 것은 의료 진단 성능에 직접적인 영향을 미치기 때문에 중요합니다. 따라서 주파수 영역에서 잡음의 통계학적인 특성을 나타내는 잡음전력스펙트럼(NPS)을 정확히 추정할 수 있어야 합니다. 전통적으로 잡음전력스펙트럼은 잡음만 포함하고 있는 영상들의 앙상블 평균으로 추정하기 때문에, 적은 양의 영상으로는 추정 오차가 증가하게 됩니다. 본 연구에서는 두 개의 기저 함수를 사용하여 팬빔 (fan-beam) CT 시스템에서 적은 양의 영상으로 정확한 잡음전력스펙트럼을 추정할 수 있는 보정 방법을 제안하였습니다. 기존의 보정 방법들 대비 각도에 따른 잡음전력스펙트럼의 정확한 진폭이 반영되었으며, 정성적·정량적 평가 모두 더 좋은 결과를 보였습니다.
  • 덧글달기
    덧글달기
       IP : 3.144.172.115

    등록