KIRAMS, 연세의대 / 권나혜, 김진성, 최상현*, 김동욱*
Abstract
A 64-channel scintillation fiber-based real-time monitoring system (SFRMS) was developed and evaluated to verify the dwell position and dwell time of the radioactive source in high-dose-rate brachytherapy. The measurement system consists of 64 sensors installed around a tandem applicator. The distal end of the readout system was fiber-optically connected to the measurement system. The data readout system consisted of a photomultiplier tube and a measurement and automation explorer. The SFRMS accuracy was evaluated in terms of dwell position, output linearity, and dwell time using an afterloader with a 192 Ir source. Additionally, a Gafchromic EBT3 film was inserted into the applicator to compare fiber measurements. Furthermore, a clinical treatment plan and silicon-based anthropomorphic phantom were utilized to evaluate the accuracy of the dwell positions and dwell times of the source in a situation mimicking a real treatment. The measured output signals from each sensor were fit with Gaussian and inverse-square functions to determine the exact source dwell positions. The difference in dwell position between the plans and the estimated data was −0.63 ± 0.25 mm for the Gaussian fitting and 0.72 ± 0.26 mm for the inverse-square fitting. The difference in dwell time between the plans and the estimated data was within 0.1 sec. For the measurements of the clinical plan on the silicon-based anthropomorphic phantom, the difference in dwell position between the plans and the estimated data was less than 0.88 ± 0.29 mm for the Gaussian fitting and less than 0.85 ± 0.36 mm for the inverse-square fitting. The SFRMS can accurately detect source dwell positions and dwell times and provide real-time output.
Affiliation
Na Hye Kwon; Jinsung Kim; Ju Hye Kim; Sang Hyoun Choi ; Dong Wook Kim
Korea Institute of Radiological and Medical Sciences, Seoul, South Korea; Yonsei University College of Medicine
편집위원
고선량률 근접방사선치료에서 삽입기구(applicator) 내 방사성선원의 머무름 위치와 시간의 정확성과 재현성은 중요한 요소이다. 본 연구에서는 64채널 섬광섬유 기반 실시간 모니터링 시스템(SFRMS)을 개발하여 치료 계획된 선원의 머무름 위치와 시간을 측정 및 성능 평가를 통하여 치료 전 환자별 계획 확인 또는 일상적인 기계적 점검을 위한 품질보증장치의 유용성을 제시하였다. 향후 삽입기구 및 섬광섬유 크기 등 보다 고도화한다면 임상 적용에 매우 유익할 것으로 기대된다.
2022-04-05 13:50:11
편집위원2
근접방사선치료에서 치료 전에 선원의 위치와 머무는 위치를 확인하는 데 이를 섬광섬유를 이용해서 쉽게 확인할 수 있는 편리한 방법을 제안한 논문이며 매우 흥미롭다.
2022-04-05 13:54:21