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  • [Phys Med Biol.] Optical imaging for the characterization of radioactive carbon and oxygen ion beams.

    NIRS / 강한규, Taiga Yamaya*

  • 출처
    Phys Med Biol.
  • 등재일
    2019 May 29
  • 저널이슈번호
    64(11):115009. doi: 10.1088/1361-6560/ab1ccf.
  • 내용

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    Abstract
    Heavy ion therapy is a promising cancer therapy technique due to the sharper Bragg peak and smaller lateral scattering characteristics of heavy ion beams as compared to a proton therapy. Recently, the potential for radioactive ion beam therapy has been investigated in combination with the OpenPET system to improve the accuracy of in vivo beam range verification. However, the characteristics of the radioactive ion beams have not been investigated thoroughly. Optical imaging has been proposed as a novel high-resolution beam range estimation method for heavy ion beams. In this study, high-resolution luminescence imaging and Cerenkov light imaging were performed for the range estimation of radioactive ion beams such as 11C and 15O in the Heavy Ion Medical Accelerator in Chiba (HIMAC) secondary beam line. A polymethyl methacrylate (PMMA) phantom (10.0  ×  10.0  ×  9.9 cm3) was irradiated by 11C and 15O ion beams. In order to obtain the in-beam luminescence and off-line beam Cerenkov light images, an optical system was used that consisted of a lens and a cooled CCD camera. The Bragg peaks and stopping positions of the 11C and 15O ion beams could be visualized by using the luminescence and Cerenkov light imaging, respectively. The Bragg peaks showed a good correlation with the peak of the luminescence profile with a positional discrepancy of 1 mm and 0.4 mm for the 11C and 15O ion beams, respectively. In conclusion, optical imaging using luminescence and Cerenkov light could be used for the precise range estimation of radioactive ion beams.

     


    Author information

    Kang HG1, Yamamoto S, Takyu S, Nishikido F, Mohammadi A, Horita R, Sato S, Yamaya T.
    1
    National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan. Author to whom any correspondence should be addressed.

  • 편집위원

    연세암병원과 서울대에서 탄소중입자치료기 도입이 되는 시점에서 실시간 비정 거리 측정이 가능한 연구 결과

    2019-07-18 15:25:13

  • 편집위원2

    최근 그리고 향후 입자빔 방사선치료가 점차 증가될 전망인데, 양성자 치료에서보다 측정에 관하여 더욱 정밀한 방법이 요구되고, 새로운 방법의 측정기술이 요구되는 실정인데, 광학적인 방법으로 비정을 정밀하게 측정할 수 있다면 매우 빠른 방법으로 정도관리를 끝냄으로서 입자빔을 사용하는 데 용이하게 되는 측면이 있을 것임

    2019-07-18 15:26:36

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