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  • [Radiat Oncol.] Reliability of the gamma index analysis as a verification method of volumetric modulated arc therapy plans.

    [Radiat Oncol.] Reliability of the gamma index analysis as a verification method of volumetric modulated arc therapy plans.

    중앙대학교병원, 원자력안전위원회 / 박종민, 오도훈*, 김상태*

  • 출처
    Radiat Oncol.
  • 등재일
    2018 Sep 14
  • 저널이슈번호
    13(1):175. doi: 10.1186/s13014-018-1123-x.
  • 내용

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    그림 1. Global gamma passing rate

    그림 2. Local gamma passing rate

     

    Abstract
    BACKGROUND:
    We investigate the gamma passing rate (GPR) consistency when applying different types of gamma analyses, linacs, and dosimeters for volumetric modulated arc therapy (VMAT).

    METHODS:
    A total of 240 VMAT plans for various treatment sites, which were generated with Trilogy (140 plans) and TrueBeam STx (100 plans), were retrospectively selected. For each VMAT plan, planar dose distributions were measured with both MapCHECK2 and ArcCHECK dosimeters. During the planar dose distribution measurements, the actual multileaf collimator (MLC) positions, gantry angles, and delivered monitor units were recorded and compared to the values in the original VMAT plans to calculate mechanical errors. For each VMAT plan, both the global and local gamma analyses were performed with 3%/3 mm, 2%/2 mm, 2%/1 mm, 1%/2 mm, and 1%/1 mm. The Pearson correlation coefficients (r) were calculated 1) between the global and the local GPRs, 2) between GPRs with the MapCHECK2 and the ArcCHECK dosimeters, 3) and between GPRs and the mechanical errors during the VMAT delivery.

    RESULTS:
    For the MapCHECK2 measurements, strong correlations between the global and local GPRs were observed only with 1%/2 mm and 1%/1 mm (r > 0.8 with p < 0.001), while weak or no correlations were observed for the ArcCHECK measurement. Between the MapCHECK2 and ArcCHECK measurements, the global GPRs showed no correlations (all with p > 0.05), while the local GPRs showed moderate correlations only with 2%/1 mm and 1%/1 mm for TrueBeam STx (r > 0.5 with p < 0.001). Both the global and local GPRs always showed weak or no correlations with the MLC positional errors except for the GPRs of MapCHECK2 with 1%/2 mm and 1%/1 mm for TrueBeam STx and the GPR of ArcCHECK with 1%/2 mm for Trilogy (r < - 0.5 with p < 0.001).

    CONCLUSIONS:
    The GPRs varied according to the types of gamma analyses, dosimeters, and linacs. Therefore, each institution should carefully establish their own gamma analysis protocol by determining the type of gamma index analysis and the gamma criterion with their own linac and their own dosimeter.

     


    Author information

    Park JM1,2,3,4, Kim JI1,2,3, Park SY5, Oh DH6, Kim ST7.
    1
    Department of Radiation Oncology, Seoul National University Hospital, Seoul, South Korea.
    2
    Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, South Korea.
    3
    Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea.
    4
    Institute for Smart System, Robotics Research Laboratory for Extreme Environments, Advanced Institutes of Convergence Technology, Suwon, South Korea.
    5
    Department of Radiation Oncology, Veterans Health Service Medical Center, Seoul, South Korea.
    6
    Department of Radiation Oncology, Myongji Hospital, Goyang, South Korea. dohoon05@gmail.com.
    7
    Nuclear Emergency Division, Radiation Protection and Emergency Preparedness Bureau, Nuclear Safety and Security Commission, Seoul, South Korea. rad21@korea.kr.

  • 키워드
    Gamma passing rate; Log file analysis; Modulation degree; Patient-specific quality assurance; Volumetric modulated arc therapy
  • 연구소개
    체적조절호형방사선치료(volumetric modulated arc therapy, VMAT)의 치료계획 검증기법으로 임상에서 가장 널리 쓰이는 감마분석기법의 신뢰도에 대하여 분석한 논문입니다. 면밀한 분석을 위해 TrueBeam STx 100 개, Trilogy 140 개(총 240 개)의 VMAT 치료계획을 분석했습니다. 감마분석을 위한 측정은 MapCHECK2와 ArcCHECK 두 가지 장비로 수행했습니다. 결과적으로 감마 passing rate은 치료계획 변조정도 이외에도 감마분석 방법(global vs. local), gamma criteria, 측정장비 타입, 선형가속기 타입 등에 영향을 받음을 확인했습니다. 따라서, 임상에서는 개별기관마다 고유의 감마분석 프로토콜을 정립해야함을 확인했습니다.
  • 편집위원

    감마통과율은 방사선선량분포를 비교할 때 그야말로 널리 사용되고 있는데, 지금까지 느낌상으로 할 때 마다 다른 것으로 예상하고 있었다. 이를 실제로 비교하여 dosimeter마다, 치료기 또는 치료기법마다 그 연관성이 다양하다는 증거를 보여주니 흥미로왔다. 좀 더 많은 데이터가 쌓이면 일반적인 개념을 도출할 수 도 있지 않을까 생각해 본다.

    2018-10-22 18:52:24

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