글로벌 연구동향
방사선종양학
- 2022년 07월호
[Asia Pac J Clin Oncol.] Influence of respiratory movement during post mastectomy radiotherapy on targets and heart for breast cancer부산의대 / 전호상, 주지현*
- 출처
- Asia Pac J Clin Oncol.
- 등재일
- 2022 Jun 2. doi: 10.1111/ajco.13773. Online ahe
- 저널이슈번호
- 내용
Abstract
Background/aim: This study aimed to compare the dosimetric consequences of respiratory movement in volumetric-modulated arc therapy (VMAT) and three-dimensional conformal radiation therapy (3D-CRT) during postmastectomy radiation therapy, including internal mammary nodes (IMNs).Materials and methods: Respiratory motion was implemented to a phantom using a dynamic device. The plans were delivered during cranial-caudal and ventral-dorsal movement in 5-mm (R05) and 10-mm (R10) amplitudes.
Results: At the IMN, the dose errors were -2.8% (R05) and -6.2% (R10) for 3D-CRT and -4.9% (R05) and -8.5% (R10) for VMAT. The dose errors in chest wall were -.5% (R05) and -6.0% (R10) for 3D-CRT and -1.9% (R05) and -5.3% (R10) for VMAT. The left anterior descending doses showed significantly small absolute values. The gamma pass rates of VMAT were higher than those of 3D-CRT.
Conclusions: The benefit of VMAT technique in dose distribution was maintained, except in occasional instances of large breathing motion.
Affiliations
Hosang Jeon 1 , Yongkan Ki 2 3 , Dong Woon Kim 3 , Wontaek Kim 2 4 , Jiho Nam 4 , Donghyun Kim 2 4 , Dahl Park 4 , Jongmoo Park 5 , Ji Hyeon Joo 2 3
1 Department of Radiation Oncology and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea.
2 Department of Radiation Oncology, Pusan National University School of Medicine, Yangsan, South Korea.
3 Department of Radiation Oncology, Pusan National University Yangsan Hospital, Yangsan, South Korea.
4 Department of Radiation Oncology, Pusan National University Hospital, Busan, South Korea.
5 Department of Radiation Oncology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, South Korea.
- 키워드
- breast neoplasm; internal mammary nodes; mastectomy; radiation therapy; respiration.
- 연구소개
- Volumetric-modulated arc therapy (VMAT) 이란, 기계가 360° 회전하는 동안 방사선량을 지속적으로 전달하는 기법으로, 주변 조직 선량을 최소화하며 종양을 효과적으로 치료합니다. 전절제술 받은 유방암 환자의 방사선 치료시, 복잡한 모양의 타겟을 호흡 움직임 하에서 치료한다는 어려움이 있습니다. 이 연구는, VMAT 의 이점이 다양한 호흡 환경 하에서 어떻게 나타나는지 소개합니다.
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